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	Provedor de dados BJMBR (3) Autor Borelli,P. (3) Blatt,S.L. (2) Fock,R.A. (2) Alvarez-Silva,M. (1) Barros,F.E.V. (1) Beutler,B. (1) Favero,G.M. (1) Nakajima,K. (1) Pereira,J. (1) Trentin,A.G. (1) Tsujita,M. (1) Vinolo,M.A.R. (1) Vituri,C.L. (1) Mais... Palavra-chave Malnutrition (3) Bone marrow (2) Blood (1) Cell cycle (1) Extracellular matrix (1) Fibronectin (1) Hemopoiesis (1) Interleukin-1β (1) Lipopolysaccharide (1) Low protein diet (1) Spleen (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2012 (1) 2009 (1) 2000 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Alterations in proteins of bone marrow extracellular matrix in undernourished mice BJMBR Vituri,C.L.; Alvarez-Silva,M.; Trentin,A.G.; Borelli,P.. The objective of the present study was to determine the effect of protein malnutrition on the glycoprotein content of bone marrow extracellular matrix (ECM). Two-month-old male Swiss mice were submitted to protein malnutrition with a low-protein diet containing 4% casein as compared to 20% casein in the control diet. When the experimental group had attained a 20% loss of their original body weight, we extracted the ECM proteins from bone marrow with PBS buffer, and analyzed ECM samples by SDS-PAGE (7.5%) and ECL Western blotting. Quantitative differences were observed between control and experimental groups. Bone marrow ECM from undernourished mice had greater amounts of extractable fibronectin (1.6-fold increase) and laminin (4.8-fold increase) when... Tipo: Info:eu-repo/semantics/article Palavras-chave: Fibronectin; Bone marrow; Extracellular matrix; Malnutrition. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000800004 Impairment of the hematological response and interleukin-1β production in protein-energy malnourished mice after endotoxemia with lipopolysaccharide BJMBR Fock,R.A.; Vinolo,M.A.R.; Blatt,S.L.; Borelli,P.. The objectives of this study were to determine if protein-energy malnutrition (PEM) could affect the hematologic response to lipopolysaccharide (LPS), the interleukin-1β (IL-1β) production, leukocyte migration, and blood leukocyte expression of CD11a/CD18. Two-month-old male Swiss mice were submitted to PEM (N = 30) with a low-protein diet (14 days) containing 4% protein, compared to 20% protein in the control group (N = 30). The total cellularity of blood, bone marrow, spleen, and bronchoalveolar lavage evaluated after the LPS stimulus indicated reduced number of total cells in all compartments studied and different kinetics of migration in malnourished animals. The in vitro migration assay showed reduced capacity of migration after the LPS stimulus in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Blood; Bone marrow; Spleen; Interleukin-1β; Lipopolysaccharide; Malnutrition. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200009 Protein-energy malnutrition halts hemopoietic progenitor cells in the G0/G1 cell cycle stage, thereby altering cell production rates BJMBR Borelli,P.; Barros,F.E.V.; Nakajima,K.; Blatt,S.L.; Beutler,B.; Pereira,J.; Tsujita,M.; Favero,G.M.; Fock,R.A.. Protein energy malnutrition (PEM) is a syndrome that often results in immunodeficiency coupled with pancytopenia. Hemopoietic tissue requires a high nutrient supply and the proliferation, differentiation and maturation of cells occur in a constant and balanced manner, sensitive to the demands of specific cell lineages and dependent on the stem cell population. In the present study, we evaluated the effect of PEM on some aspects of hemopoiesis, analyzing the cell cycle of bone marrow cells and the percentage of progenitor cells in the bone marrow. Two-month-old male Swiss mice (N = 7-9 per group) were submitted to PEM with a low-protein diet (4%) or were fed a control diet (20% protein) ad libitum. When the experimental group had lost about 20% of their... Tipo: Info:eu-repo/semantics/article Palavras-chave: Malnutrition; Hemopoiesis; Cell cycle; Low protein diet. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600008 Registros recuperados: 3 Primeira ... 1 ... Última

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